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Ben Stiller portrays risk-averse Reuben Feffer, whose best-laid plans for life and love zoom wildly off track when his wife (Messing) dumps him on their honeymoon for a scuba instructor (Azaria). Stunned, humiliated and in the grip of acute indigestion, Reuben plans to play it safer than ever. But a chance encounter with an adventure-craving, globe-trotting friend from middle school (Aniston) shoots him into a whirlwind of extreme sports, spicy foods, ferrets, salsa dancing and living in the mom
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